Yellow nail syndrome

V. Kowsalya; Sonia Agrawal; Chander Grover

doi:10.25259/JONS_12_2024

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Onychoterminology (Typical Clinical or Onychoscopic Sign)

1 (

1

); 49-50

doi:

10.25259/JONS_12_2024

Yellow nail syndrome

V. Kowsalya¹_MBBS., Sonia Agrawal¹_{MD., DNB.}, Chander Grover^1,_{MD., DNB.}

1Department of Dermatology and STD, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India.

*Corresponding author: Dr. Chander Grover, MD. DNB, FAMS, FIAD, Director Professor, Department of Dermatology and STD, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India. chandergroverkubba76@gmail.com

Received: 2024-08-21, Accepted: 2024-09-11, Published: 2024-11-29

Licence

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

How to cite this article: Kowsalya V, Agrawal S, Grover C. Yellow nail syndrome. J Onychol Nail Surg. 2024;1:49-50. doi: 10.25259/JONS_12_2024

CASE DETAILS

A 13-year-old male presented with thickened, hard, yellow finger- and toenails for 5 years. He had a history of recurrent sinusitis. Nails showed xanthonychia [Figure 1a], pachyonychia, and increased transverse curvature, with Grade 2 onycholysis and subungual hyperkeratosis [Figure 1b]. Chest X-ray was normal. Based on clinical findings, a diagnosis of yellow nail syndrome (YNS) was made. The patient was treated with fluconazole (150 mg weekly), Vitamin E (400 mg BD) and antibiotics for sinusitis.

(a) Clinical image showing yellowish discolouration (xanthonychia) and thickening (pachyonychia) of multiple nails with an increased curvature. Cuticles are absent in multiple nails. (b) Close-up view of both thumbnails showing pachyonychia and xanthonychia. The left thumbnail shows greenish discolouration as well as a circular biopsy site.

DESCRIPTION

YNS may present as isolated nail changes, cough/sinusitis, lymphoedema, or severe life-threatening conditions, including pleural effusion. Although there is no cure, symptomatic management and thorough screening with regular follow-up help identify complications early.

Authors’ contributions

All the authors contributed to the manuscript preparation and design of the study, acquisition of data, analysis, and interpretation of data, drafting the article and revising it clinically for important intellectual content and final approval of the submitted version.

Ethical approval

Institutional Review Board approval is not required.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consents.

Conflicts of interest

Dr. Chander Grover is on the editorial board of the Journal.

Use of artificial intelligence (AI)-assisted technology for manuscript preparation

The authors confirm that there was no use of artificial intelligence (AI)-assisted technology for assisting in the writing or editing of the manuscript and no images were manipulated using AI.

Financial support and sponsorship

Nil.